1. Pro-Xylane Overview
Where to buy Pro-Xylane with reasonable price and high quality? Where to find good information of wholesale Pro-Xylane? As the professional Pro-Xylane manufacturer, BFSTAR is your best choice.
Pro-Xylane, also known as hydroxypropyl tetrahydropyrantriol, is a glycoprotein mixture derived from xylose. Since xylose exists in large quantities in beech trees, it has the ability to promote the production of glucosaminoglycans, namely mucopolysaccharides (GAGs). Also, xylose can provide binding sites for GAGs, start the generation and assembly of GAGs in the skin, and improve the deficiency of GAGs caused by skin aging. Studies have shown that Pro-Xylane is easy to biodegrade, does not accumulate in organisms, and has no toxicity.
BFSTAR develops 2 kinds of Pro-Xylane, 30% liquid and 98% powder. Both are water-soluble It can be used in skincare products for anti-aging.
| Product Name | CAS Number | INCI Name | |
| Pro-Xylane | 439685-79-7 | HYDROXYPROPYL TETRAHYDROPYRANTRIOL | |
| Molecular Weight | Molecular Formula | Molecular Structure | |
| 192.21g/mol | C8H16O5 |
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| Product ID | Specification | Minimal Package | Minimal Order Quantity |
| BFSTAR2001 | 30% liquid | 1kg | 1kg |
| BFSTAR2002 | 98% powder | 100g | 100g |
2. Pro-Xylane Source
The inventor of Pro-Xylane, Dr. Maria DALKO-CSIBA, a scientist at the L’Oreal R&D and Innovation Center, is based on this characteristic of xylose, using a large number of beech and birch trees that exist in nature. In 1999-2000, he led the team to synthesize more than 200 kinds of xylose derivatives. Based on comprehensive consideration of factors such as efficacy, safety, stability and skin bioavailability, Pro-Xylane was finally successfully screened out. Nowadays, Pro-Xylane mainly obtained by chemical synthesis.
3. Pro-Xylane Manufacturer Specifications
30% Liquid Specifications
| Items | Specification |
| Hydroxypropyl tetrahydropyrantriol | ≥30% |
| Boric acid | ≤3.0% |
| Appearance | Colorless clear liquid |
| Odor & taste | Characteristic |
| Physical Characteristics | |
| Luminousness | ≥90% |
| Heavy Metals | |
| Pb | ≤10ppm |
| As | ≤2ppm |
| Hg | ≤1ppm |
| Cd | ≤5ppm |
| Microbiological Tests | |
| Total plate count | ≤100cfu/g |
| Yeast & mold | ≤10cfu/g |
| Coliform | Negative |
| Salmonella | Negative |
| Staphylococcus aureus | Negative |
98% Powder Specifications
| Items | Specification |
| Hydroxypropyl tetrahydropyrantriol | ≥98% |
| Appearance | White to light yellow powder |
| Physical Characteristics | |
| Loss on drying | ≤3.0% |
| Heavy Metals | |
| Pb | ≤10ppm |
| As | ≤2ppm |
| Hg | ≤1ppm |
| Cd | ≤5ppm |
| Microbiological Tests | |
| Total plate count | ≤100cfu/g |
| Yeast & mold | ≤50cfu/g |
| Coliform | Negative |
| Salmonella | Negative |
| Staphylococcus aureus | Negative |
4. Pro-Xylane Benefits
- Anti-aging
Studies have proved that Pro-Xylane can exert biological effects at different layers of the skin
- Acting on the epidermis, Pro-Xylanecan promote the synthesis of various GAGs, and at the same time up-regulate the expression of hyaluronic acid receptor CD44 and syndecan, thereby activating the signal pathway mediated by GAGs. Clinical studies have shown that topical application of Pro-Xylane can effectively reduce transepidermal water loss, improve skin barrier function, and promote epidermal renewal, making the skin plump and radiant.
- At the Dermal-Epidermal Junction (DEJ), Pro-Xylanecan up-regulate collagen type IV (the main component of the lamina densa), laminin, type VII collagen (the main component of anchoring fibrils) and other key proteins. Then it can induce the expression of proteoglycanperlecan, and strengthen the tightness and stability of DEJ structure. Clinical studies have shown that in aging skin samples, the ultra-microscopic structure of DEJ presents the aging characteristics in several areas. After local application of Pro-Xylane, the DEJ structure of aging skin can be made more uniform and clear, the re-duplication of lamina densa is significantly reduced, making the skin structure stronger.
- In the dermis, Pro-Xylanecan promote the production of various GAGs such as hyaluronic acid and heparan sulfate. In addition, the up-regulation of the expression of type I procollagen and fibrillin-1 is observed, suggesting that the production of GAGs and collagen. They are both important dermal extracellular matrix components that maintain skin elasticity and firmness. Therefore, it has been proved in clinical research that topical application of Pro-Xylane can effectively improve the fine lines and wrinkles of the skin, and make the skin firm and elastic.
- Skin Repair
In vitro skin experiments, Pro-Xylane is able to reconstruct the complete structure of the epidermodermal layer, and it also had similar function as retinoic acid, enhancing the thickness of the stratum corneum and providing barrier function, but without irritation.
5. BFSTAR Pro-Xylane Characteristics
- No irritating odor, no toxicity, low content of acetic acid and borate, won’t affect the formulation.
- Good water solubility and stability, not easy oxidation, easily absorbed by skin.
6. Pro-Xylane Application and Reference Dosage
Pro-Xylane is mainly used in anti-aging, skin repair, anti-wrinkle skincare products, such as serum, facial mask, emulsion, toner, essence, cream, etc.
| Product | Reference Dosage |
| 30% Pro-Xylane | 0.2%-3% in leave-on cosmetics |
| 0.3-5% in wash-off cosmetics | |
| 98% Pro-Xylane | 0.5%-2% |
Pro-Xylane application cases in major cosmetic brands in the world:
| Brand | Product |
| L’Oreal |
RevitaLift Triple Power Eye Treatment
Revitalift Triple Power Intensive Anti-Aging Moisturizer |
| SkinCeuticals |
Hyaluronic Acid Intensifier Hydrating Serum
A.G.E. Interrupter Moisturizer |
| Biotherm | Homme Force Supreme Lotion |
| La Roche-Posay |
Substiane Serum
Substiane [+] UV SPF 15 Hyalu B5 Hyaluronic Acid Eye Cream |
| Estee Lauder | RE-NUTRIV Ultimate Lift Regenerating Youth Serum |
| LANCOME |
Absolue demaquillant gel
ABSOLUE L’EXTRAIT ULTIMATE EYE CONTOUR COLLECTION ABSOLUE REVITALIZING EYE SERUM Absolue White Aura |
| KIEHL’S |
Hydrating & Clarifying Treatment Masque
KIEHL’S Clearly corrective dark spot solution |
| Vichy |
Neovadiol Compensating Complex Night Cream
Neovadiol complexe substitutif day cream IDEALIA DAY CARE |
7. Pro-Xylane Safety
- CTFAhas recognized HYDROXYPROPYL TETRAHYDROPYRANTRIOL as a raw material for cosmetics;
- The International Catalogue of Chinese Cosmetic Raw Materials Standardsin 2018 issued by HYDROXYPROPYL TETRAHYDROPYRANTRIOL.
- On the Announcement of Name List of Cosmetics Raw Materialpublished by CFDA in 2021 both include HYDROXYPROPYL TETRAHYDROPYRANTRIOL.
8. Package and Storage
Package: 1kg/bag, 1kg/bottle
Storage: Store in cool and dry place at room temperature, keep away from strong light.
